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Year : 2010  |  Volume : 4  |  Issue : 2  |  Page : 45-50

Amyotrophic lateral sclerosis

S.S.D.J. College of Pharmacy, Neminagar, Chandwad, - 423 101, (M.S.), India

Correspondence Address:
V S Gulecha
S.S.D.J. College of Pharmacy, Neminagar, Chandwad, MS - 423 101
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0331-3131.78270

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Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder with no effective treatment. It occurs when specific nerve cells in the brain and spinal cord that control voluntary movement gradually deteriorate. The loss of these so-called motor neurons causes the muscles under their control to weaken and waste away, leading to paralysis. ALS varies from patient to patient, depending on which muscles weaken first. ALS strikes in mid-life and it is observed that men are about one-and-a-half times more likely to have the disease as women. The present review is an attempt to give an insight into the signs, symptoms, diagnosis and symptomatic treatment of ALS.

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