Prevalence of malaria among HIV patients on highly active antiretroviral therapy in Kogi State, North Central Nigeria
Frederick Olusegun Akinbo1, Peter Joel Anate2, David Bolaji Akinbo2, Richard Omoregie3, Stephen Okoosi4, Abubakar Abdulsalami5, Banabas Isah6
1 Department of Medical Laboratory Science, School of Basic Medical Sciences, University of Benin, Benin City, Nigeria
2 Department of Medical Laboratory Science, Achievers University, Owo, Ondo State, Nigeria
3 School of Medical Laboratory Sciences, University of Benin Teaching Hospital, Benin City, Nigeria
4 Ministry of Health, General Hospital, Obangede, Nigeria
5 Ministry of Health, Zonal Hospital, Okene, Nigeria
6 Ministry of Health, Okene, Kogi State, Nigeria
Frederick Olusegun Akinbo
Department of Medical Laboratory Science, School of Basic Medical Sciences, University of Benin, Benin City
Source of Support: None, Conflict of Interest: None
Background: Malaria and HIV diseases kill millions of people yearly, and they are the scourges of developing nations. This study was conducted to determine the coinfections of malaria and HIV, and the effect of demographic characters on HIV-infected patients receiving highly active antiretroviral therapy (HAART) in Kogi State, Nigeria.
Methods: Five hundred and eleven participants consisting of 411 (51 males and 360 females) HIV-infected patients on HAART and 100 (8 males and 92 females) apparently healthy HIV-noninfected individuals who served as controls were enrolled in this study. Blood sample was collected from each participant and malaria was diagnosed using the standard procedure.
Results: An overall prevalence of 7.8% and 2% of malarial infection was observed in HIV-infected patients on HAART and non-HIV participants, respectively. The prevalence of malaria among HIV patients on HAART differed signifi cantly (P < 0.0001) among the local government councils, with patients from Ogori-Magongo having the least prevalence (0.0%). Age, gender, type of occupation, clinical manifestations, anemia, and CD4+ T-cell count <200 cells/μL affected the prevalence of malarial infection (P < 0.05) in this study.
Conclusion: Diagnosis of malaria among HIV patients on HAART is advocated.